Antibiotic prophylaxis is a preventative measure, often used in dentistry to prevent infective endocarditis. This involves the administration of antibiotics prior to dental procedures to prevent the growth of bacteria in the blood stream.

Explanation: Antibiotic prophylaxis is an important topic in dentistry, especially when it comes to preventing infective endocarditis. To provide a detailed answer, let's break down the question and the use of antibiotic prophylaxis in dentistry.

The question asks: When should antibiotic prophylaxis be used in dentistry?

1. Purpose of Antibiotic Prophylaxis:
Antibiotic prophylaxis is a preventative measure, often used in dentistry to prevent infective endocarditis. This involves the administration of antibiotics prior to dental procedures to prevent the growth of bacteria in the blood stream. When bacteria enter the bloodstream during a dental procedure, they can attach to heart valves and cause infective endocarditis. Antibiotics help prevent this from happening by stopping the growth of harmful bacteria.

2. Who Should Receive Antibiotic Prophylaxis?
Antibiotic prophylaxis is typically recommended for people who have certain heart conditions or have received certain types of heart surgery. These individuals are at a higher risk for developing infective endocarditis. Examples of heart conditions or heart surgeries that might require antibiotic prophylaxis include:

a) Congenital heart disease: Patients with congenital heart defects may have abnormal heart valves or blood vessels that make them more susceptible to endocarditis.

b) Prior heart valve replacement: Patients who have previously undergone a heart valve replacement surgery are at an increased risk of developing infective endocarditis.

c) Mitral valve prolapse: Patients with mitral valve prolapse are also at an increased risk of developing endocarditis and may require antibiotic prophylaxis.

d) Prior heart surgery: Patients who have had heart surgery, such as coronary artery bypass grafting (CABG), may require antibiotic prophylaxis as well.

3. When Should Antibiotic Prophylaxis Be Used in Dentistry?
The need for antibiotic prophylaxis is determined by the risk level of developing infective endocarditis. This risk level is typically determined by the severity of the heart condition or heart surgery. In general, antibiotic prophylaxis is recommended for procedures that are considered more invasive or likely to cause bleeding, such as:

a) Extractions or tooth removal: Removing teeth can cause bleeding and potentially allow bacteria to enter the bloodstream, increasing the risk of endocarditis. Antibiotic prophylaxis is recommended for patients at high risk.

b) Surgery on the gums or supporting structures of the teeth: Procedures like periodontal surgery, gingival surgery, or flap surgery can cause bleeding and increase the risk of endocarditis. Antibiotic prophylaxis may be recommended for patients at high risk.

c) Certain types of dental implant placement: Patients at high risk may require antibiotic prophylaxis before placing dental implants or performing certain types of dental implant surgeries.

d) Invasive procedures involving the tooth roots: Root canal treatments, apicoectomies, and procedures involving the root apex of the tooth may require antibiotic prophylaxis for patients at high risk.

4. Dosage and Frequency of Antibiotic Prophylaxis:
The dosage and frequency of antibiotic prophylaxis depend on the individual's condition and the procedure being performed. Patients should follow their dentist's or physician's recommendations for antibiotic prophylaxis and make sure to take the full course of antibiotics as prescribed. Typically, antibiotic prophylaxis is taken one hour before the dental procedure and one hour after.

5. Safety and Potential Side Effects of Antibiotic Prophylaxis:
Like any medication, antibiotic prophylaxis can have side effects, and patients should discuss these with their healthcare provider. Common side effects include diarrhea, stomach pain, or an upset stomach, but can vary based on the specific antibiotic used. It's important to note that antibiotic prophylaxis is not recommended for every patient and should be discussed with a doctor or dentist before any dental procedure.

In conclusion, the use of antibiotic prophylaxis in dentistry is a preventative measure to reduce the risk of infective endocarditis. Antibiotic prophylaxis is recommended for patients with certain heart conditions or those who have previously undergone heart valve replacements or certain heart surgeries. Antibiotic prophylaxis should be taken before certain invasive dental procedures, but it's essential to discuss the risks and benefits with a dentist or healthcare provider.